The 17th chapter of Isaiah is the denunciation of Damascus and Israel. But like most prophecies, although the setting is in ancient times the prophetic message pertains to the time of the end.
That ought to be evident from the concluding part of the prophecy, which says: “Ha for the commotion of many peoples, who are boisterous as with the boisterousness of the seas! And for the noise of national groups, who make a din just like the noise of mighty waters! The national groups themselves will make a din just like the noise of many waters. And He will certainly rebuke it, and it must flee far away and be chased like the chaff of the mountains before a wind and like a thistle whirl before a storm wind.”